Status:
ReviewerMember since: 2019
Organization: Teva
Novel method/instrument but not reproducible.
Application Area: Particle analysis in biotech products
"Its principle of operation is novel. However, the reproducibility is poor and therefore the data my not be reliable in many cases. But its an important characterization tool for biotech products in pre-filled syringes."
Manufacturer's ResponseThank you for your feedback. I’m sorry to hear that you are not finding your data reproducible. We would be happy to review your measurement method to aim to improve this with you. There is also a very good paper that could help you ensure that you obtain the best possible data for your biotherapeutic sample: Product Characterization. Kreuger A, Hadley J et al. J Pharm Sci 108 (2019) 1675-1685.
Status:
ReviewerMember since: 2019
Organization: Sanofi
A good supplement to flow imaging microscopy but expensive.
Application Area:Particle characterization (silicone oil vs. proteinaceous particles)
"We use the device for further characterization of small particles observed with flow imaging microscopy. The main application is the distinction between positive and negative buoyancy masses. This application works well and we rarely have problems with big particles clogging a capillary as we characterize the samples before the Archimedes measurements and can treat the samples accordingly. For the additional information obtained the price for the device is quite high."
Status:
ReviewerMember since: 2016
Organization: Takeda Pharmaceutical
Instrument did not generate any data and is considered un-repairable now
Application Area:Pharmaceutical biologics
"This instrument did not generate any data after the purchase. The problem was constant clogging and hardware failure. Finally, Malvern engineer deemed it un-repairable and unusable. Thus, purchasing this instrument was a waste of money since there was no return for its value Not easy to use. Constant clogging. Not reliable"
Status:
ReviewerMember since: 2016
Organization: Takeda
I wish I could return this instrument.
Application Area:Differentiate silicone and protein particles
"This machine has never been functional for long. Have had glass vials explode and sensor port catch fire. Very displeased with overall function."