ApoE Knockout Rat by SAGE Labs
In vivo model for cardiovascular, alzheimer’s and other neurodegeneration studies.
Apolipoprotein E (ApoE) is a critical apoprotein of the chylomicron which binds to a specific receptor on liver cells and peripheral cells. Defects in ApoE result in disrupted transportation of lipoproteins, fat-soluble vitamins and cholesterol into the lymph systems, and then into blood.ApoE Knockout Rat Characteristics:
16 bp deletion within Exon 3 on chromosome 1
Homozygous knockouts exhibit complete los...
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