Annexin V : FITC Apoptosis Detection Kit I by BD Biosciences
Manufacturer BD Biosciences
Apoptosis is a normal physiologic process which occurs during embryonic development as well as in maintenence of tissue homeostasis. The apoptotic program is characterized by certain morphologic features, including loss of plasma membrane asymmetry and attachment, condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA. Loss of plasma membrane is one of the earliest features. In apoptotic cells, the membrane phospholipid phosphatidylserine (PS) is translocated from the in... Read more
Annexin V : FITC Apoptosis Detection Kit I
Average Rating: 4.5
2 Scientists have reviewed this product
Status:
Advanced Reviewer
Member since: 2019
Organization: washington University
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- Ease of use
- After sales service
- Value for money
This is working great.
Rating: 5.0
Application Area: Analyse apoptosis of IELs
"This works very specifically to stain and score apoptosis. The process is very easy and user freindly."
Review date: 21 Jun 2021 | Annexin V : FITC Apoptosis Detection Kit I
Status:
Reviewer Member since: 2013
Organization: Thomas Jefferson University
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- Ease of use
- After sales service
- Value for money
Rating: 4.0
Review date: 18 Feb 2014 | Annexin V : FITC Apoptosis Detection Kit I
Application Area:Flow
"This apoptosis detection kit is easy to use."
Review date: 18 Feb 2014 | Annexin V : FITC Apoptosis Detection Kit I
Apoptosis is a normal physiologic process which occurs during embryonic development as well as in maintenence of tissue homeostasis. The apoptotic program is characterized by certain morphologic features, including loss of plasma membrane asymmetry and attachment, condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA. Loss of plasma membrane is one of the earliest features. In apoptotic cells, the membrane phospholipid phosphatidylserine (PS) is translocated from the inner to the outer leaflet of the plasma membrane, thereby exposing PS to the external cellular environment. Annexin V is a 35-36 kDa Ca2+ dependent phospholipid-binding protein that has a high affinity for PS, and binds to cells with exposed PS (reviewed in 1). Annexin V may be conjugated to fluorochromes such as Propidium Iodide (PI). This format retains
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