Status:
Advanced ReviewerMember since: 2009
Organization: Harvard Medical School - ICCBL
Great support and awesome instrument
Application Area: Analysis of cytotoxicity
"The Acumen is highly effective at getting us the results that we want and is fairly easy to use once a protocol is set up on the instrument. The only issues that I have with it are that some of the functions of the software are harder to find than I believe necessary (e.g. how to tell how many cells are in each well while that program is running) and that the machine is very finicky in the fact that if anything in the machine is bumped or a little loose it can make the whole program go down. Other than that, the support is great (my emails are always answered within 24 hours) and for the most part the machine runs pretty smoothly."
Status:
ReviewerMember since: 2009
Organization: Harvard Medical School
Application Area:Academic compound and RNAi HTS
"The Acumen Cellista is a flexible platform that enables a wide range of fluorescence assays, from common cell/bead counting and total fluorescence measurements to specialized whole organism imaging and 3D cell culture applications. Cellista offers the highly qualitative data of a ~4X imager with the speed of a typical multimode plate reader. Laser excitation and a large depth of field reliably capture even low expression fluorophores without the need to focus on each well. Cellista is less suited for subcellular resolution imaging nor trying to segment confluent cells, though. The images can also be taken as TIFFs and analyzed in other software suites. Ease of use: My facility functions as a staff assisted HTS/equipment core, and I find that I am able to train most users to operate the instrument independently within 1-3 hours. The Cellista software package is very powerful yet approachable to end users. After Sales Care: TTPLabtech has excellent after-sales care. The customer-vendor relationship continues well beyond the purchase, and the support is fast and efficient. Difficult questions are automatically advanced to the appropriate engineer and answers are quick to follow. TTPLabtech being a UK-based company, I was initially concerned that support is 6 hours ahead, but the US team is excellent and I am now convinced that some of the UK folks are either nocturnal or simply don’t sleep. Value for Money: This is a tricky question. The Acumen is immensely valuable in an HTS environment and traffic and demand on the instrument are high and only continue to grow in my facility. It does come with a nontrivial price tag, and there are cheaper (slower) high content scopes on the market. Still, I would definitely recommend the Acumen Cellista for applications benefiting from speed, sensitivity and ease of use."
Status:
ReviewerMember since: 2011
Organization: AstraZeneca
"This is a good product for rare events. I like the multiple lasers however would have prefered to do less training."
Status:
ReviewerMember since: 2011
Organization: Nih
"We use Acumen for HTS screening. The read times are somewhat slow, but the quality of data is good. The sales support is good, but sometimes can be slow."
Status:
ReviewerMember since: 2011
Organization: Nih-Ncgc
"Excellent plate reader (pmt base). Flow cytometer for 1536 well plate formats. Reasonable image quality but good for fluorescence cell based assay. Drawback: need additional lasers for mulitplexing."
acumen® Cellista – the fastest high content screening system.
acumen Cellista is a microplate-based laser scanning imaging cytometer designed to provide rapid, whole well, content-rich cytometric and image based analysis. It has your high content screening data imaged and ready in as little as 5 minutes, making it the fastest HCS system available today.
acumen is the go-to system for phenotypic screening, where it complements existing imaging expertise and maximises workflow throughputs. It images the whole well and provides both cytometric data and open source TIFFs allowing rapid, content rich data to identify compounds of interest. Where number of compounds screened is critical, wells of interest can be selected for more in depth analysis using the TIFF images.
Benefits of acumen Cellista include:
acumen can be used as part of several types of workflow:
acumen Cellista has been proven to be a highly successful screening platform in the field of oncology based on assays that can be performed in the following areas:
Manufacturer SPT Labtech | Available Worldwide
4.4 / 5.0 | 8 reviews