Action Potential Duration (APD) Testing on hESC-Derived Cardiomyocytes

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Action Potential Duration (APD) Testing on hESC-Derived Cardiomyocytes
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Evaluate compounds in human stem cell-derived, ventricular-type cardiomyocytes. Effects on action potential parameters are evaluated in single human cardiomyocytes using patch-clamp recording
Benefits:

  • Human ion channels expressed in a native cardiac environment
  • Detects AP Prolongation (QT risk) and EADs (Torsade trigger)
  • Stable recordings at physiological temperature with minimal diffusion delays
  • Cost-effective
  • Rapid turnaround time

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Description

Evaluate compounds in human stem cell-derived, ventricular-type cardiomyocytes. Effects on action potential parameters are evaluated in single human cardiomyocytes using patch-clamp recording
Benefits:

  • Human ion channels expressed in a native cardiac environment
  • Detects AP Prolongation (QT risk) and EADs (Torsade trigger)
  • Stable recordings at physiological temperature with minimal diffusion delays
  • Cost-effective
  • Rapid turnaround time

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Action Potential Duration (APD) Testing on hESC-Derived Cardiomyocytes

by ChanTest Corporation

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