Action Potential Duration (APD) Testing on hESC-Derived Cardiomyocytes by ChanTest Corporation
Evaluate compounds in human stem cell-derived, ventricular-type cardiomyocytes. Effects on action potential parameters are evaluated in single human cardiomyocytes using patch-clamp recording Benefits:
Human ion channels expressed in a native cardiac environment
Detects AP Prolongation (QT risk) and EADs (Torsade trigger)
Stable recordings at physiological temperature with minimal diffusion delays
Cost-effective
Rapid turnaround time
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