The ACQUITY UPLC® M-Class System with HDX Technology leverages UPLC® separations and high-resolution MS to answer important questions about changes in protein conformation including:
The unprecedented system-level design integrates all the steps necessary to accurately, reproducibly, and most of all, easily, perform protein conformation studies. The system and its DynamX™ HDX Analysis Software removes the barriers to adopting high resolution LC and MS for routine studies of protein conformational changes, making hydrogen deuterium exchange with MS (HDX, HDX MS, HXMS, or H/D exchange) a core competency for your laboratory.
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