ACQUITY UPC² System

ACQUITY UPC² System
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by Waters
 4.2/5.0 (10 reviews)

Convergence Chromatography with the ACQUITY UPC² System Bring streamlined workflow, expanded selectivity, and an orthogonal technique to your laboratory. Convergence chromatography (CC) is a broad-based, complementary analytical platform that is taking its place alongside of LC and GC as one of the three essential separation technologies for modern laboratory analysis. This technique provides...read more

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Reviews

AVERAGE RATING: 4.2

10 scientists have reviewed this product

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  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY

Jana Kralova


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Member since 2013

Organization:
University of Amsterdam
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 08 Aug 2013

ACQUITY UPC² System

"Very useful equipment. Waters service is in my opinion the best from all the HPLC equipment companies."

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Sunil Dubey


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Member since 2013

Organization:
Birla Institute of Technology and Science (BITS)
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RATING: 3.7

  • 3 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 08 Aug 2013

Application Area: protein analysis
ACQUITY UPC² System

"This is really an excellent high throughput system. We are enjoying working on it. After sales service is good too. A rugged and robust system. The speed is matchless. However, it could be made more user friendly."

Pieter Kooijman


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Member since 2013

Organization:
Vrije Universiteit
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: Analysis of complex bio-mass samples
ACQUITY UPC² System

"A very complete system, with possibilities currently available on the market. After finding your way around the software it is no more than turning it on and injecting for top chromatograms."

Katalin Ganzler


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Member since 2013

Organization:
Gedeon Richter Plc.
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: pharmaceutical analysis
ACQUITY UPC² System

"Saves money on eluent and development time. Very good service. Too pricey in Hungary though compared to US prices."

Dennis Drost


Status:


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Member since 2013

Organization:
UvA
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RATING: 4.7

  • 5 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: bio oil analysis
ACQUITY UPC² System

"The UPC system is easy to use with a user friendly interface. Optimization of the gradient to get the best chromatogram was easy to do and a good chromatogram was quickly recorded. Also the other properties like pressure and detector specs were easily adjusted. The sales person also came by to see if we had questions and to give us some insights into easier ways to use the software. Overall it was easy to learn to use the software to its full extent and the technique itself has a lot of possibilities."

Noortje de Haan


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Member since 2013

Organization:
Vrije Universiteit
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RATING: 4.0

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 3 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: Complex bio-oil samples
ACQUITY UPC² System

"The software was very easy to use. Also the device itself was straight forward in its applicability. It was a good apparatus for the project."

Nandor Lambert


Status:


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Member since 2013

Organization:
PTE-TTK
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RATING: 4.3

  • 5 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: Analysis of mass-transfer
ACQUITY UPC² System

"Good software and the best hardware. Bit difficult but usable software for data acquisition and data analysis. Robust, reproducible and compact hardware."

Peter Vajda


Status:


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Member since 2013

Organization:
University of Tennessee
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RATING: 4.3

  • 5 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 29 May 2013

Application Area: preparative supercritical fluid chromatography
ACQUITY UPC² System

"Excellent performance of the CO2 pump, minimize the effect of the density change of the mobile phase through the column on the chromatographic data. The software is easy to use and helps perform the necessity. The sales service is excellent, except the speed of the response. The instrument is bit expensive, but maybe worth it."

Bhavisha Patel


Status:


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Member since 2013

Organization:
Bristol Myers Squibb
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RATING: 3.7

  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 3 out of 5VALUE FOR MONEY




Review date: 29 May 2013

Application Area: Analytical
ACQUITY UPC² System

"Very easy to order; I am very impressed that they provide me services after I received my last order. I would recommend having this for a long time."

Christopher Howson


Status:


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Member since 2013

Organization:
Novartis
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RATING: 4.0

  • 3 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 20 May 2013

Application Area: Pharmaceutical analysis
ACQUITY UPC² System

"The UPC2 system is Waters first attempt at a SFC system that is truly theirs rather than making use of inherited equipment from previous acquisitions. It fits nicely in amongst the Acquity family of instruments and makes use of pre-existing Acquity features which familiar users will be pleased with (SFC modules integrated into Acquity Console). Running the system through MassLynx is not only straight forward but provides an easy platform for MS integration. From my experiences the hardware has been performing very well and I would highly recommend this instrument to anyone looking to do high resolution/high throughput chiral or achiral analysis."

Description

 

Convergence Chromatography with the ACQUITY UPC² System

Bring streamlined workflow, expanded selectivity, and an orthogonal technique to your laboratory.

Convergence chromatography (CC) is a broad-based, complementary analytical platform that is taking its place alongside of LC and GC as one of the three essential separation technologies for modern laboratory analysis. This technique provides another, reliable choice as an analytical platform that is orthogonal to reversed-phase LC (RPLC), while significantly streamlining the entire analytical workflow.

In convergence chromatography, the separation is achieved by manipulating the density and composition of a supercritical fluid-based mobile phase. Because of the very high diffusivity of the mobile phase, can be achieved. Additionally, the diversity of stationary phase and mobile phase (co-solvent) options provides access to the largest selectivity space available to any separation technique.

The ACQUITY UPC² System is a holistically designed UltraPerformance Convergence Chromatography (UPC²) system that utilizes liquid CO2 as the primary mobile phase. The system leverages the chromatographic principles and selectivity of normal-phase chromatography while providing the ease-of-use of RPLC, enabling you to address routine and complex separations challenges.

ACQUITY UPC² System: Discover what's been missing from your analytical toolbox

With the ACQUITY UPC² System, scientists can now separate, analyze, and understand compounds that have challenged all other LC and GC technologies including:

  • Hydrophobic and chiral compounds
  • Lipids
  • Thermally-labile samples
  • Polymers

It's also the perfect complement to MS due to its low solvent load and high resolution, narrow peaks and fast separations.

ACQUITY UPC² System Features:

  • Compressed carbon dioxide (CO2), the primary mobile phase, is less costly and less toxic than liquid mobile phases or carrier gases.
  • Variable volume injection delivers 0.5 µL to 10 µL as well as the ability to match column and injection volume with minimal sample loss and need to change loops.
  • Higher throughput and productivity allows you to analyze more samples per day with faster re-equilibration of columns and shorter cycle times, increasing laboratory productivity.
  • Co-solvent and column switching provides flexibility in method development for faster solvent screening and faster column screening.

Application notes and news

Product Overview

ACQUITY UPC² System by Waters
ACQUITY UPC² System




  • 4out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY





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