The novel column chemistry of the Thermo ScientificAcclaim® Mixed-Mode WAX-1 results in a multimode separation mechanism including hydrophobic, anion-exchange, and cation-exclusion interactions. Consequently, retention of basic, neutral, and acidic molecules can be either independently or concurrently adjusted by changing ionic strength, pH, and organic solvent content in the mobile phase.
Features:
Adjustable selectivity
Selectivity orthogonal to reversed-phase (RP) columns
Ideal selectivity for anionic molecules
Simultaneous separation of acidic, basic, and neutral molecules
Multimode retention mechanisms: reversed- and normal phase, anion-exchange, cation-exclusion, and HILIC mode
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