Thermo Scientific™ Acclaim® Mixed-Mode HILIC-1 LC Column

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The Acclaim® Mixed-Mode HILIC-1 column utilizes a unique silica-based, mixed-mode stationary phase that combines both reversed-phase (RP) and hydrophilic interaction liquid chromatography (HILIC) properties.

The column functional group features a hydrophobic alkyl chain and hydrophilic diol functionality. This combination allows both hydrophobic interaction and hydrophilic interaction to be utilized to optimize separations.

The Acclaim Mixed-Mode HILIC-1 columns consist of 5 μm high-purity, porous, spherical silica with 120 Å-diameter pores bonded with proprietry functional groups, which provide unsurpassed resolution and peak symmetry for a variety of polar and nonpolar molecules.

Acclaim® Mixed-Mode HILIC-1 LC Column Features:

  • Operates in both RP and HILIC modes
  • Retains highly polar molecules
  • Unique selectivity complementary to RP columns
  • Superior performance compared to conventional diol-based columns
  • High efficiency column for high resolution separations

Column Details:

  • Chemistry: Proprietary alkyl diol
  • Particle Size: 5 µm
  • Pore Size: 120 Å
  • Length: 50, 150, 250 mm
  • ID: 2.1, 3.0, 4.6 mm

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Thermo Scientific™ Acclaim® Mixed-Mode HILIC-1 LC Column

Manufacturer Thermo Fisher Scientific

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