Leveraging the historically stable fluidic design of the original MoFlo and the electronic processing of the MoFlo XDP, the MoFlo Astrios expands sorting capabilities with a full palette of laser options. Seven pinholes spatially separate each laser, providing the flexibility and expandability known to MoFlo sorting.
The MoFlo Astrios is the new standard for cell sorting with functionality, speed, and improved sensitivity. It is designed for researchers who desire high productivity with more analytical capability and with biosafety solutions. The ergonomic design of Astrios makes it faster and easier to operate. All components requiring operator control are within easy reach.
Beyond the optic expansion, novel software components enhance the instruments capabilities. The Touch Screen Control Panel facilitates daily set up with its operation designed around core laboratory workflow. Auto Start Up enables the user to pre-define when the lasers and fluidics will start up, saving valuable time each morning. Creating flat-top beam profiles, a multi-fiber Beam Shaping Optic (BSO) shortens alignment time and improves optic stability. Two stages control the alignment for all 7 lasers, simplifying the sorter preparation.
Auto QC allows system performance to be tracked and trended across 32 available parameters. IntelliSort II is a fully bead-less drop delay determination and monitoring system. Camera images and proprietary algorithms enable the optimal drop delay to be determined without the use of fluorescent particles in the sample line. An updated version of Summit Software containing 6-way sorting, plate sorting up to 1536-well, and Index sorting logic is standard. The Quick Release nozzle design enables removal or swapping of the nozzle body and tip through the use of single lever.
Designed from the start with biosafety considerations, MoFlo Astrios has comprehensive aerosol evacuation design that filters particles from all chambers where aerosols have the potential of being generated. A fully sealed sort chamber housing the redesigned R-Theta CyClone arm facilitates the aerosol evacuation capabilities which are tested to the current ISAC guidelines. Additionally, the MoFlo Astrios has a custom Biosafety Level II cabinet option. The BSL II cabinet is tested to NSF-49 International standards with the MoFlo Astrios inside.