The ASIC1a gene encodes the pore-forming subunit of a proton-gated, non-selective cation channel. ASIC1a channels expressed in neurons are therapeutic targets for treatment of pain and depression.
Synonyms: Acid-sensing (proton-gated) ion channel Host cell: CHO-K1, division-arrested Gene name: ACCN2 Mycoplasma status: Negative (MycoAlert Kit) Packaging: Three vials of Cryopreserved irradiated cells, 2x106 cells/vial (6x106 cells total) Growth media: Ham’s F12; 10% FBS Growth characteristics: cells remain viable 1–2 days post-thaw Storage recommendation: frozen under liquid nitrogen Functional expression: median current amplitude = 2.5 nA Recommended assay: manual or automated patch clamp
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