Chromatin Immunoprecipitation (ChIP) is an important technique allowing the researcher to analyze in vivo interactions of proteins with genomic DNA. Any chromatin-associated or DNA binding protein can be analyzed with this technique, provided a good antibody to the protein exists. One can measure different proteins localized to a specific region of the genome, or the genome wide distribution of a specific protein. Another powerful application of this technique is to analyze changes in histone modifications that correlate with processes like transcription, mitosis or DNA repair.
Features & Benefits:
/u Spin columns make DNA purification easier and more reliable - no more messy phenol-chloroform extractions.
/u All reagents to process your samples are included - you don't have to spend valuable time making them.
/u Positive and negative control antibodies and PCR primers are included to help validate your results and to troubleshoot your experiments.