6400 Series Triple Quadrupole LC/MS by Agilent Technologies

4.5
/
5.0
  |  35 reviews

Meet your quantitative needs with triple quadrupole performance that gives you superior sensitivity, renowned reliability, and overall system robustness. Agilent 6400 Series Triple Quadrupole LC/MS Systems are proven choices for quantitative applications in: Pharmaceutical ADME/DMPK studies Biomarker validation Clinical research Food testing Forensics Toxicology Environmental analyses.


6400 Series Triple Quadrupole LC/MS by Agilent Technologies product image
6400 Series Triple Quadrupole LC/MS
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Average Rating: 4.5
35 Scientists have reviewed this product

4 out of 5
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Advanced Reviewer
  • Member since: 2022

  • Organization: Amrita school of pharmacy



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Good results and very effective in the field of organic synthesis
Rating: 4.0

  • Application Area: Chemical analysis and organic synthesis

"It's is having high sensitivity and give data on ultra concentration upto 1ppm, also have advance LC which works under ultra high pressure and reduce the run time for samples."

Review date: 28 Mar 2023 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Corteva



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Robust, sensitive (ppt levels), easy to run
Rating: 5.0

  • Application Area:Analysis of hormones in plasma

"The Agilent 6495A is a very robust and sensitive instrument for the analysis of hormones in plasma. Able to see down to ppt levels for many hormones. The instrument is very robust and easy to use. Have used competitors triple quads and not achieved the sensitivity that is possible on the 6495. This instrument has been a great addition to the lab. Easy to run robust and great value too compared to other systems."

Review date: 28 Sep 2022 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: GfL Gesellschaft für Lebensmittel-Forschung mbH



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Precision and accuracy
Rating: 4.0

  • Application Area:Analyse pesticides and vitamins

"It is an easy-to-use instrument and leads to precise and reproducible results. It has a user friendly interface."

Review date: 28 Sep 2022 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Rwanda Forensic Laboratory



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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It is powerful and sensitive Technology
Rating: 4.3

  • Application Area:Analysis of drugs, pesticides, poisons and metabolites

"It is very sensitive and powerful technology. The results are reliable and reproducible."

Review date: 10 Jun 2022 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: University of Guadalajara



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Without the instrument you cannot get results
Rating: 5.0

  • Application Area:Analyze metabolites in biological fluids

"The instrument is expensive to acquire, it is expensive to maintain, its consumables are expensive. The technology it provides is one of the best and latest generation, the results are great and allow progress in research."

Review date: 24 May 2022 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: TUV SUD



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent equipment
Rating: 5.0

  • Application Area:Analytical department in Food testing lab

"Easy to handle and works excellent"

Review date: 14 Apr 2022 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: TUV SUD



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent working
Rating: 5.0

  • Application Area:Analytical department in Food testing lab

"Excellent Equipment"

Review date: 30 Mar 2022 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: TUV SUD



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great result and excellent technical suupport
Rating: 5.0

  • Application Area:Analytical department in Food testing lab

"Excellent Product"

Review date: 26 Mar 2022 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Erp, Narc



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Excellent results
Rating: 4.3

  • Application Area:Pesticides residue

"Easy to use, accuracy of results, and friendly software"

Review date: 07 Feb 2022 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Nutrasynth LLC



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Gives you great results and reports!
Rating: 4.3

  • Application Area:Sample profile testing

"Agilent has quality instruments, easy to use software, and good support of intruments. They have good technical support. Good price for machines."

Review date: 02 Feb 2021 | 6400 Series Triple Quadrupole LC/MS


  • Status:

    Reviewer

  • Member since: 2020

  • Organization: University of Dundee



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great sensitivity.
Rating: 5.0

  • Application Area:Protein quantification

"Easy to use, no issues at all."

Review date: 17 Dec 2020 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: US Dept Agriculture



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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The state labs using this equipment love it.
Rating: 4.3

  • Application Area:Pesticides in foods

"Great system to have for laboratories testing pesticides in foods."

Review date: 18 Nov 2020 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: RotaChrom Technologies LLC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, low maintenance, pretty easy to use.
Rating: 5.0

  • Application Area:Analyze natural products

"No major problems so far, with regard to precision and reproducibility. It is a great instrument for our purposes."

Review date: 17 Jun 2020 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University For Development Studies



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Provides accurate and reliable results.
Rating: 4.0

  • Application Area:Analyze blood in sample

"The product is good. Easy to understand and use. It produce accurate and reliable results as expected. There has been no waste of money or resources from acquiring it. It is highly recommenable to other users"

Review date: 26 Apr 2020 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Eurofins analytical services pvt ltd



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Easy analysis with this instrument.
Rating: 4.7

  • Application Area:Pesticide residue analysis

"I have been using it since 2014 and have found it very suitable for my analyses. Method optimization, method validation, quantification and review of results processes are easy for the user. It is a user friendly instrument."

Review date: 09 Mar 2020 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Advanced Reviewer

  • Member since: 2020

  • Organization: UIC



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Very user-friendly.
Rating: 4.0

  • Application Area:LC-MS

"The triple quad does a great job at separatng/fragmenting the parent ion of interest with enough resolution to identify the parent ion using known databases. Very user-friendly."

Review date: 06 Mar 2020 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Gvkbio



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Super.
Rating: 5.0

  • Application Area:Small molecules

"Good for research and development, small and big molecules."

Review date: 13 Dec 2019 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: ARCHROMA INDIA PRIVATE LIMITED



  • Ease of use
    3 out of 5
    After sales service
    2 out of 5
    Value for money
    1 out of 5
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Good results but not good value for money.
Rating: 2.0

  • Application Area:Analyze dyes and chemicals

"Very effective for my testing, response very good. Value for money not good. Frequently failure in hardware. Most of the electronic boards need to be replace within two years time. Service cost is also too high."

Review date: 20 Nov 2019 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Institute for Bioscience and Biotechnology



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good instrument
Rating: 5.0

  • Application Area:Protein quantification

"The 6490 QQQ is a quite easy to use the instrument. I first started with zero experience on QQQ but got comfortable with this instrument after very short period of training. The data we obtained are easy to analyze either with the manufactural software or Skyline. We did once have issues with the calibration and low sensitivity right after PM (not sure what happened, but a service engineer came to fix/replace some parts and since then the instrument is behaving great."

Review date: 03 Nov 2017 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: iict



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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SENSITIVITY AND RUGGEDNESS
Rating: 4.0

  • Application Area:CLINICAL DIAGNOSTICS

"This system is ideal for regular quantification of metabolomics"

Review date: 03 Aug 2017 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Expert Reviewer

  • Member since: 2015

  • Organization: university of cambridge



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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5 Star Servicing
Rating: 5.0

  • Application Area:Targetted Proteomics

"Agilent offers brilliant packages for service contracts for Mass Spectrometry. We have two Agilent Mass Specs in our lab and have taken the silver contract with them. The response time for a logged call is 48 hours and there is hardly any time where they delayed in getting back to us. Their field scientist are well trained and know what they are doing. I have learnt a lot while they are on call at our facility. I would definitely recommend the equipment and service contracts from them. They also offer cross lab service contracts."

Review date: 11 Jan 2017 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: CDPH



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very good instrument. We got good results to support out bio-monitoring program.
Rating: 5.0

  • Application Area:environmental analysis

"conducted trace analysis for "Measurement of Urinary Dialkyl Phosphate Metabolites of Organophosphorus Pesticides". It is a good instrument."

Review date: 11 Nov 2016 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Nu Skin Enterprises



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
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Wish it had fewer automated processes that the user cannot control.
Rating: 3.7

  • Application Area:Mass spectrometry analysis of bioactive analytes and contaminants in nutraceutical products.

"The 6490 mass spectrometer has standard MS/MS scan capabilities, but is really designed and intended for a novice user. Many features for the operation of the instrument are automated, which is perhaps good for an inexperienced user. However, a mass spectrometrist is limited by what the software will allow. For example, tuning, resolution adjustment, and calibration are relatively restricted to automated procedures, rather than allowing the operator to adjust and set the instrument as desired. Sensitivity of the instrument is average or below, compared to other triple-quad instruments on the market, particularly negative-ion experiments. The instrument also has somewhat unstable ionization."

Review date: 24 Mar 2016 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Portsmouth University



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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very good machine, works great
Rating: 4.0

  • Application Area:Analyze metaldehyde from water sample

"Utilizing our new improved method, we have reach a highly sensitive way of analyzing low levels of metaldehyde within water. Using the Agilent 6400 LC/MS QQQ this has been accomplished, only problems which have occurred is with the maintenance as this can become problematic when organizing availability of engineers "

Review date: 24 Feb 2016 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: IMB-Mainz



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0

  • Application Area:Quantify the ammounts of different DNA bases in genomic DNA ( DNA adducts and epigenetic marks)

"The Instrument was purchased about 2 years ago, at this time it showed best sensitivity for nucleoside detection if compared to to triple Q models of Thermo, Waters, or Absciex at this time ( LOD ~20 fmols). We are a scientific group but have ran the instrument day and night since the purchase. It runs with minor technical problems, some can be solved by us, some require parts replacement and done by the service engineer one or two days after the call. It maintains the calibration over weeks or even months, requiring minor attention for cleaning and re-calibration. In general Agilent instruments are very well engineered and manufactured and this is instrument is one of such examples. We are very satisfied with its performance."

Review date: 29 Jul 2015 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Abu Dhabi Forensic Laboratory



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0
"Easy auto tune, very easy to use Mass Hunter Software, easy maintenance and works very hard. Thanks Agilent for excellent products."

Review date: 02 Jul 2015 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Expert Reviewer

  • Member since: 2013

  • Organization: JRFAmerica



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Rating: 4.3

  • Application Area:Residue and E-fate Metabolism chemistry

"It is a very robust instrument with high sensitivity, it has not totally proven it self in the Residue chemistry area but I think it has a lot of potential to be one of the best. The software needs some work but the Mass hunter has put Agilent with the best. It is easy to clean and maintain. One negative is that sometimes you have some variability between sample injections but it is compound dependent. I recommend this instrument for Environmental analysis, and some residue studies."

Review date: 02 Jan 2014 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: US Food and Drug Administration



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Rating: 4.3

  • Application Area:Chemical analysis of food and drugs

"Easy to use with helpful training. Good after sales service with fast, professional response and troubleshooting."

Review date: 26 Mar 2012 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: AUT University



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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Rating: 3.7
"A good product but too expensive in my opinion."

Review date: 15 Jul 2011 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: FDA



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0
"The 6460 is easy to use and Agilent has good service."

Review date: 21 Jun 2011 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: FDA



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0
"Agilent have good service. The 6430 is easy to use but switching out columns can be a hassle and the computer wasn't as compatible as it should have been."

Review date: 21 Jun 2011 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: University Of Illinois



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Rating: 4.3
"Very user friendly interface."

Review date: 20 Jun 2011 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Duquesne University



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 4.7
"Service after sale is excellent. Reps were always helpful and able to resolve problems quickly."

Review date: 20 Jun 2011 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: Chang Gung University



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
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Rating: 3.7

Review date: 06 Jul 2009 | 6400 Series Triple Quadrupole LC/MS
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: City of Hope



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 4.7

Review date: 06 Jul 2009 | 6400 Series Triple Quadrupole LC/MS

Meet your quantitative needs with triple quadrupole performance that gives you superior sensitivity, renowned reliability, and overall system robustness. Agilent 6400 Series Triple Quadrupole LC/MS Systems are proven choices for quantitative applications in:

  • Pharmaceutical ADME/DMPK studies
  • Biomarker validation
  • Clinical research
  • Food testing
  • Forensics
  • Toxicology
  • Environmental analyses.