4000 QTRAP®  LC/MS/MS System

Manufacturer SCIEX
4.2
/
5.0
  |  25 reviews


Product Image



Average Rating: 4.2
25 Scientists have reviewed this product

4 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money
  • Status:

    Expert Reviewer

  • Member since: 2013

  • Organization: Pharmazentrum, University Of Basel



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Bioanalysis

"The most used triple quadrupole in the area of bioanalysis and still a very sensitive system even if you have the new systems on the market: API 5500, API 6500. The API 4000 QTRAP is very useful for metabolic studies especially C14 studies. Getting a second hand system is quite easy. I would advise to just use a front end HPLC or UPLC from shimadzu."

Review date: 20 Dec 2013 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2008

  • Organization: ANSTO



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

  • Application Area:Chemical and biological deuteration of organic molecules

"It is easy to use and is very useful for getting a quick MS to monitor the level of deuteration achieved during the course of a reaction. The accuracy is high enough to enable calculation of percentage deuteration."

Review date: 12 Aug 2013 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Montreal's Forensic Lab / Concordia University



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 3.7

  • Application Area:Forensic Toxicology

"Good instrument to perform targeted analysis (e.g. by MRM). It can handle many transitions at the same time (our method has over 120 and it works well). However there are several problems with the Analyst software that have not been solved even in the 1.6 version (frequent crash, turbo heaters suddenly stop working and you have to re-save the method...)."

Review date: 28 May 2013 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Missouri University of Science and Technology



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.7

  • Application Area:water research

"I utilize the AB sciex 4000 Qtrap on a daily basis, in an LC-MS set up. This instrument set up for easy set up and ran by beginners. This was my first MS to ever run solo, and it was quick to pick up and utilize with the software. We utilize this set up for water research and it works great. It also requires minimal maintenance."

Review date: 20 May 2013 | 4000 QTRAP®  LC/MS/MS System


  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Panacea Biotec Ltd.



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:Bioanalytical

"The system shows excellent sensitivity but is not that reproducible. It is very rugged and provides excellent value for money."

Review date: 26 Apr 2012 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Massachusetts Institute of Technology



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.7

  • Application Area:LC-MS Quantification

"Easy to use and maintain and good value. Reliable hardware, delivers the results you expect. The software is ok but not stable. It freezes very frequently but easy to use."

Review date: 23 Mar 2012 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Advanced Reviewer

  • Member since: 2009

  • Organization: Dept. of Health and Mental Hygiene, Maryland



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"Reliable, user friendly software. Good, friendly on-site tech support."

Review date: 04 Jul 2011 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2008

  • Organization: ANSTO



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0
"The mass spectrometer has very high sensitivity and the analyst software is very user friendly."

Review date: 01 Jul 2011 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2005

  • Organization: Cephalon France



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3

Review date: 27 Jun 2011 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Bio Analytical Technologies India (P) Ltd



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.7
"Very nice instruments for bioanalysis, impurity identification, metabolite identification and charcterisation."

Review date: 27 Jun 2011 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Emory Institute for Drug Discovery



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.7
"The software is poorly designed."

Review date: 31 May 2011 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Advanced Reviewer

  • Member since: 2010

  • Organization: Amgen



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

Review date: 17 Feb 2010 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Advanced Reviewer

  • Member since: 2010

  • Organization: Amgen



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

Review date: 17 Feb 2010 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: Virginia Commonwealth University



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 4.7
"A great product."

Review date: 06 Jul 2009 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: Mass Spectrometry Applications to the Clinical Laboratory



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Rating: 4.3

Review date: 06 Jul 2009 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Advanced Reviewer

  • Member since: 2009

  • Organization: University of Kentucky



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0

Review date: 06 Jul 2009 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: Oregon State University



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"A work horse of an instrument."

Review date: 01 Jul 2009 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2008

  • Organization: Rudolf Virchow Center For Experimental Biomedicine



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.7

Review date: 11 Sep 2008 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2008

  • Organization: CHILDRENS HOSPITAL LOS ANGELES-USC



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 3.7
"an excellent system for lipidomics, but it does require training and is quite pricey."

Review date: 01 Jul 2008 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Dalian Institute of Chemical Physics



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 4.0

Review date: 18 Oct 2007 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Budapest University of Technologies



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Rating: 3.7

Review date: 28 Aug 2007 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2004

  • Organization: UCLA Olympic Analytical Laboratory



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Rating: 3.7

Review date: 09 Feb 2007 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Merck Frost



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.0
"Excellent instrument and sensitivity."

Review date: 28 Apr 2006 | 4000 QTRAP®  LC/MS/MS System
  • Status:

    Reviewer

  • Member since: 2005

  • Organization: Pfizer



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Rating: 3.3
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Review date: 15 Jul 2005 | 4000 QTRAP®  LC/MS/MS System

The 4000 QTRAP® LC/MS/MS System is AB SCIEX's premier Hybrid Triple Quadrupole/Linear Ion trap mass spectrometer. Ideal for drug discovery and development, metabolite identification, contaminant testing, and proteomic applications including post-translationally modified proteins discovery, protein identification, and biomarker validation.

Features of the 4000 QTRAP® LC/MS/MS System:

  • Enables high-sensitivity full-scan MS, MS/MS, and MS3 with high-selectivity from true triple quadrupole precursor ion (PI) and neutral loss (NL) scans.
  • Perform multiple reaction monitoring (MRM) for quantitation using high-sensitivity triple quadrupole.
  • Identify, characterize, and quantitate metabolites more quickly and easily.
  • Identify and sequence post-translationally modified (PTM) peptides automatically in a single LC/MS/MS run.
  • Facilitates hypothesis-driven biomarker discovery and validation.