- Ease of use
- After sales service
- Value for money
Description
The 4000 QTRAP® LC/MS/MS System is AB SCIEX's premier Hybrid Triple Quadrupole/Linear Ion trap mass spectrometer. Ideal for drug discovery and development, metabolite identification, contaminant testing, and proteomic applications including post-translationally modified proteins discovery, protein identification, and biomarker validation.
Features of the 4000 QTRAP® LC/MS/MS System:
- Enables high-sensitivity full-scan MS, MS/MS, and MS3 with high-selectivity from true triple quadrupole precursor ion (PI) and neutral loss (NL) scans.
- Perform multiple reaction monitoring (MRM) for quantitation using high-sensitivity triple quadrupole.
- Identify, characterize, and quantitate metabolites more quickly and easily.
- Identify and sequence post-translationally modified (PTM) peptides automatically in a single LC/MS/MS run.
- Facilitates hypothesis-driven biomarker discovery and validation.
Application notes and news
- Advanced Automated Library Searching for Compound Identification in Forensic Toxicology Samples
- MRM3 Quantitation for Highest Selectivity in Complex Matrices
- High Throughput Metabolic Stability Screening with MALDI Triple Quadrupole Mass Spectrometry
- An Automated High Throughput Approach to Permeability Screening using MDCK Monolayers and Rapid LC/MS/MS An...
- Strategies to Identify and Confirm Phase I Metabolites of Glyburide Using the 4000 Q TRAP™ System
- Workhorse Mass Spectrometer for Routine Quantitation and Screening
Reviews
Manish Kumar Status: See all reviews Member since 2010 Organization: Panacea Biotec Ltd. Read more » | RATING: 4.6 
"The system shows excellent sensitivity but is not that reproducible. It is very rugged and provides excellent value for money."   |
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| Tao Ye Status: See all reviews Member since 2010 Organization: Massachusetts Institute of Technology Read more » | RATING: 4.6
"Easy to use and maintain and good value. Reliable hardware, delivers the results you expect. The software is ok but not stable. It freezes very frequently but easy to use." |
| Raji Ravi Status: See all reviews Member since 2009 Organization: Dept. of Health and Mental Hygiene, Maryland Read more » | RATING: 5.0
"Reliable, user friendly software. Good, friendly on-site tech support." |
| Greta Moraes Status: See all reviews Member since 2008 Organization: ANSTO Read more » | RATING: 4.0
"The mass spectrometer has very high sensitivity and the analyst software is very user friendly." |
| Gilbert Moachon Status: See all reviews Member since 2005 Organization: Cephalon France Read more » | RATING: 4.3
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| Navnath Jaybhaye Status: See all reviews Member since 2007 Job Title: Research Scientist / Senior / PI Discipline: ADME / DMPK Work Field: Pharmaceuticals / Biopharmaceuticals Organization: Bio Analytical Technologies India (P) Ltd Read more » | RATING: 4.6
"Very nice instruments for bioanalysis, impurity identification, metabolite identification and charcterisation." |
| Prabhakar Gruddanti Status: See all reviews Member since 2011 Organization: Emory Institute for Drug Discovery Read more » | RATING: 3.6
"The software is poorly designed." |
| Wale Rufai Status: See all reviews Member since 2010 Organization: Amgen Read more » | RATING: 5.0
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| Wale Rufai Status: See all reviews Member since 2010 Organization: Amgen Read more » | RATING: 5.0
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| Dayanjan Wijesinghe Status: See all reviews Member since 2009 Organization: Virginia Commonwealth University Read more » | RATING: 4.6
"A great product." |
| David Herold Status: See all reviews Member since 2009 Organization: Mass Spectrometry Applications to the Clinical Laboratory Read more » | RATING: 4.3
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| Manjula Sunkara Status: See all reviews Member since 2009 Organization: University of Kentucky Read more » | RATING: 4.0
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| Jeff Morre Status: See all reviews Member since 2009 Organization: Oregon State University Read more » | RATING: 4.3
"A work horse of an instrument." |
| René Zahedi Status: See all reviews Member since 2008 Organization: Rudolf Virchow Center For Experimental Biomedicine Read more » | RATING: 3.6
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| MIN KANG Status: See all reviews Member since 2008 Organization: CHILDRENS HOSPITAL LOS ANGELES-USC Read more » | RATING: 3.6
"an excellent system for lipidomics, but it does require training and is quite pricey." |
| Guowang Xu Status: See all reviews Member since 2006 Organization: Dalian Institute of Chemical Physics Read more » | RATING: 4.0
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| Blanka Toth Status: See all reviews Member since 2007 Organization: Budapest University of Technologies Read more » | RATING: 3.6
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| Borislav Starcevic Status: See all reviews Member since 2004 Organization: UCLA Olympic Analytical Laboratory Read more » | RATING: 3.6
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| Wayne Mullett Status: See all reviews Member since 2006 Organization: Merck Frost Read more » | RATING: 4.0
"Excellent instrument and sensitivity." |
| Xiaoli Wang Status: See all reviews Member since 2005 Organization: Pfizer Read more » | RATING: 3.3
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