Status:
Expert ReviewerMember since: 2013
Organization: ONCODESIGN
Application Area:Bioanalysis
"The most used triple quadrupole in the area of bioanalysis and still a very sensitive system even if you have the new systems on the market: API 5500, API 6500. The API 4000 QTRAP is very useful for metabolic studies especially C14 studies. Getting a second hand system is quite easy. I would advise to just use a front end HPLC or UPLC from shimadzu."
Status:
ReviewerMember since: 2008
Organization: ANSTO
Application Area:Chemical and biological deuteration of organic molecules
"It is easy to use and is very useful for getting a quick MS to monitor the level of deuteration achieved during the course of a reaction. The accuracy is high enough to enable calculation of percentage deuteration."
Status:
ReviewerMember since: 2013
Organization: Montreal's Forensic Lab / Concordia University
Application Area:Forensic Toxicology
"Good instrument to perform targeted analysis (e.g. by MRM). It can handle many transitions at the same time (our method has over 120 and it works well). However there are several problems with the Analyst software that have not been solved even in the 1.6 version (frequent crash, turbo heaters suddenly stop working and you have to re-save the method...)."
Status:
ReviewerMember since: 2013
Organization: Missouri University of Science and Technology
Application Area:water research
"I utilize the AB sciex 4000 Qtrap on a daily basis, in an LC-MS set up. This instrument set up for easy set up and ran by beginners. This was my first MS to ever run solo, and it was quick to pick up and utilize with the software. We utilize this set up for water research and it works great. It also requires minimal maintenance."
Status:
ReviewerMember since: 2010
Organization: Panacea Biotec Ltd.
Application Area:Bioanalytical
"The system shows excellent sensitivity but is not that reproducible. It is very rugged and provides excellent value for money."
Status:
ReviewerMember since: 2010
Organization: Massachusetts Institute of Technology
Application Area:LC-MS Quantification
"Easy to use and maintain and good value. Reliable hardware, delivers the results you expect. The software is ok but not stable. It freezes very frequently but easy to use."
Status:
ReviewerMember since: 2007
Organization: Bio Analytical Technologies India (P) Ltd
"Very nice instruments for bioanalysis, impurity identification, metabolite identification and charcterisation."
The 4000 QTRAP® LC/MS/MS System is AB SCIEX's premier Hybrid Triple Quadrupole/Linear Ion trap mass spectrometer. Ideal for drug discovery and development, metabolite identification, contaminant testing, and proteomic applications including post-translationally modified proteins discovery, protein identification, and biomarker validation.
Features of the 4000 QTRAP® LC/MS/MS System: