AequoScreen® Parental cells stably expressing the mitochondrially targeted apoaequorin and the G-protein Gα16 for flash-luminescence assay. Recombinant, in 1321N1 host cell. GPCRs of your choice c...read more
AequoScreen® Parental cells stably expressing the mitochondrially targeted apoaequorin and the G-protein Gα16 for flash-luminescence assay. Recombinant, in 1321N1 host cell. GPCRs of your choice can be transiently / stably transfected into these cell lines. Following GPCR stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal. Two vials of cryopreserved cells are shipped per order.
Functional, homogenous and generic assay platform for Gs and Gi coupled GPCRs
Fully automatable and miniaturizable to 1536
Enables reduction in reagents and consumable costs
High signal to background ratio enabling detection of agonists, antagonists and allosteric modulators
Robust assay (Z, CV values, solvent resistance)
Reduces the number of false positives from autofluorescent compounds in screening libraries
Option to work with cells in suspension to increase throughput
Write a review
Sharing your experience will help scientists like you. Achieve Reviewer Status and Win an iPad air (All reviews published will be entered into the next drawing on March 30th 2014).
Join the Global SelectScience Community Today! It’s FREE!
Helping you make informed decisions about the latest lab products and technologies:
Be the first to learn about new technologies
10,000+ trusted product reviews from your peers
Compare 500,000 products and manufacturers
Get exclusive buying tips from experts
Find solutions fast: 10,000+ Application Notes, Webinars and Videos
Connect with 250,000 scientists... All in one place!