QIAGEN N.V. has announced further validation of the GeneReader NGS System with the publication of five new independent studies that reaffirm the analytical performance and ease in using the world’s first complete Sample to Insight solution that makes the benefits of next-generation sequencing (NGS) accessible to any laboratory.
The studies*, which are being presented this week at the Global Congress on Molecular Pathology (AMP Global 2017) in Berlin, demonstrated the performance of the GeneReader System in oncology research applications to generate insights from cancer tumor samples collected from both FFPE (formalin-fixed paraffin-embedded) and non-invasive liquid biopsies. The studies also reviewed implementation of the complex NGS technology, and that the GeneReader NGS System was identified as a feasible solution that can be replicated by laboratories with limited resources. (The current version of the GeneReader NGS System is for Research Use Only.)
“These findings from users in the United States and Europe show the value of the GeneReader NGS System as a simple, cost-effective way for laboratories around the world to take advantage of this powerful technology. In a variety of cancers and sample types, these studies show the GeneReader System compares well against alternative platforms and offers unique benefits as the only fully integrated NGS workflow,” said Dr. Kai te Kaat, Vice President and Head of QIAGEN’s Oncology Franchise in the Molecular Diagnostics Business Area. “Our Sample to Insight solution provides everything a lab needs for a complete end-to-end NGS workflow, and one that offers increasing flexibility and utility with the range and we will continue to demonstrate the utility of the GeneReader System to achieve actionable insights.”
Among the independent customer abstracts published at the AMP Global Berlin conference:
In addition, three abstracts are being presented that were submitted by QIAGEN teams and partners:
During 2017, QIAGEN is rolling out system enhancements designed to significantly improve the utility, efficiency and cost-effectiveness of the GeneReader NGS System. These include plans for at least five new GeneRead QIAact gene panels compatible with both FFPE and liquid biopsies. In a move that will significantly broaden the use for oncology research applications, QIAGEN also plans to soon offer services to customers for the development of customized gene panels for use on the GeneReader NGS System. QIAGEN’s gene panels have also been upgraded to incorporate the proprietary Digital NGS technology that enables more accurate quantification and detection of variants in samples. The GeneReader NGS System is being expanded to analyze a broader range of genetic variant types that include large rearrangements (in particular exon-skipping events), gene fusions and copy number variations (CNVs), in addition to current capabilities for single nucleotide polymorphisms (SNPs), gene expression and genomic insertions or deletions (InDels).
*Some data contained in these scientific works may have been created using legacy chemistry or may reference such data. Legacy chemistry is available outside the United States only. Upgraded chemistry is available to customers in the United States.