Roche Launches New Cedex Bio HT Analyzer for Cell Fermentation Process Analytics
29 Oct 2012

Roche has announced the global launch of its Cedex Bio HT Analyzer for the highly reliable determination of metabolites and substrates in mammalian and microbial cell fermentation. The Cedex Bio HT System offers very precise analytics, a broad test portfolio allowing flexible adaption of additional test menus as well as very good convenience thanks to a highly automated platform processing up to 120 tests per hour.

Designed for high-throughput applications such as in-process development, its data can be directly compared with data produced by Cedex Bio and Cedex Bio HT Analyzers located worldwide, making these instruments ideal for high scale manufacturing in a global biotech production network. Furthermore, customers benefit from Roche's established global technical service and application support network.

“The Cedex Bio HT Analyzer sets a new gold standard in bioprocess analytics. Its precise test results and high data consistency help to create optimal conditions for fermentation processes, which in turn result in high product quality and yield.” said Ruedi Stoffel, Head of Custom Biotech at Roche. “The Cedex Bio HT Analyzer is able to deliver the high data precision and reproducibility for critical process parameters that are essential to the successful implementation of authority’s regulations in biopharmaceutical production. As a result, one of our early customers entirely switched to the Cedex Bio and new Cedex Bio HT Analyzers in their biomanufacturing network”

By minimizing hands-on-time, the Cedex Bio HT Analyzer demonstrates greater precision, sensitivity and linearity than instruments that use membrane-based technology. It includes three different measuring methods enabling the analysis of IgG (immunoglobulin G) in addition to LDH (lactate dehydrogenase) and various substrates and metabolites as glutamate, glutamine, sodium, potassium, glucose, lactate and ammonia.
 

Roche now supplies reliable systems for all types of in-process control of fermentation processes using mammalian and microbial cells in the form of its Cedex Bio Analyzer for low-throughput and its new Cedex Bio HT Analyzer for high-throughput applications. To obtain even more comprehensive in-process manufacturing information, Roche recommends combining its Cedex Bio instruments with its Cedex HiRes Cell Analyzers.

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