LI-COR® Biosciences has teamed up with Molecular Targeting Technologies, Inc. to offer PSVue® 794 a near-infrared fluorescent probe for researchers who have the need to detect bacteria, apoptotic and necrotic cells, or other anionic membranes for in vivo or in vitro use.
LI-COR Releases New Probe to Detect Apoptosis and Bacterial Infections
“PSVue 794 binds to the phosphatidylserine (PS) residues exposed on the cell surface of apoptotic cells, making it a more cost-effective alternative to fluorescently labeled Annexin V for various cell death assays,” says Shawn Mischnick, LI-C0R technical product specialist. “This probe is also suitable for high-throughput screening assays.”
PSVue 794 binds to a variety of cell types that have negatively charged phospholipids exposed on their membranes, including necrotic cells, Gram-negative and Gram-positive bacteria, activated cells, tumor vascular endothelial cells, and viruses. The near-infrared fluorescent signal can be imaged on the LI-COR Pearl® Impulse or Odyssey® CLx Imaging System.
Company websiteLI-COR Biosciences