Adaptive Designs in Clinical Trials


SMi is proud to present its 8th annual Adaptive Designs in Clinical Trials conference, held in central London on the 24 & 25 March 2014.

Hear through case studies how all sizes of pharmaceutical companies have successfully implemented trials incorporating adaptive designs. This conference is the only in Europe that focuses on adaptive designs specifically, providing delegates with updates on recent developments in enrichment design, dose response modeling, computer simulation, internal and external regulatory expectations and new data on evaluating adaptive dose ranging studies.

Adaptive Designs in Clinical Trials 2014 aims to show you how you can quickly and accurately implement an adaptive design clinical trial for your drug development - from initial processes in managing trials to choosing the right time to implement change

• Learn from Michael Krams how to create an environment where adaptive designs can become the norm
• The only conference in Europe to focus specifically on adaptive designs in clinical trials
• Benefit from the first-hand experiences of speakers whose organizations have recently made breakthroughs in adaptive designs
• Hear from Vladimir Anisimov the very latest on predicative analytical techniques for increasing efficiency of drug development
• Discover at our post conference workshop how FACT software that supports the ever increasing complexity of adaptive clinical trials works, hosted by Tom Parke of Tessella
• Michael Krams, MD, Global Head, Quantitative Sciences, Janssen Pharmaceutical Companies of Johnson & Johnson
• Vladimir Anisimov, Senior Strategic Biostatistics Director, Quintiles
• Roger Lewis, MD, PhD, Senior Medical Scientist, Berry Consultants
• Loïc Darchy, Head of Statistical Methodology Group, Sanofi R&D
• Lilla Di Scala, Senior Statistical Scientist, Roche
• Pantelis Vlachos, Principle Biostatistician, Strategic Consulting, Cytel Corporation
• Sue Todd, Professor of Medical Statistics, University of Reading
• Frank Fleisher, Principal Statistician, Boehringer-Ingelheim
• Christopher Jennison, Professor of Statistics, University of Bath
• Graeme Archer, Statistics Director, GlaxoSmithKline

Workshop A: Simulating Clinical Trials using the FACTS software package: Why simulate clinical trials, how to simulate clinical trials and the difference it will make. Wednesday 26th March 2014 | Holiday Inn Regents Park, London, UK |8.30am – 1.00pm. Workshop Leader: Tom Parke, Head of Clinical Trial, Solutions, Tessella Ltd

Workshop B: Identifying and Exploiting Opportunities for Efficiency in Clinical Trial Design: An Interactive Adaptive Design Workshop. Wednesday 26th March 2014 | Holiday Inn Regents Park, London, UK | 1.00pm - 5.00pm. Workshop Leader: Professor Roger J. Lewis, MD, PhD, Senior Medical Scientist, Berry Consultants

For more information on this conference click on the event website or contact Ruth Christianson at +44 20 7827 6062 or email

Holiday Inn Regents Park

Organizer: SMi Group Ltd

24 Mar 2014

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