Editorial Article: Free Webinar: New Bio-Inert Hardware and LC bioZen Column Supports Biosimilar and Protein Characterization Complexity

Find out how you can save you time, avoid any issues with reproducibility, and improve both the robustness and quality of methods and data

17 May 2018


When performing analytical LC method development for proteins, priming of columns before analysis can be labor and time intensive, and often result in reproducibility and carryover concerns. A novel bio-inert column hardware has been designed to mitigate these problems and improve the quality of results by advancing levels of characterization.

As the complexity of biotherapeutics and biosimilars continues to increase, so too have the levels of characterization needed. To support this shift, Phenomenex has designed an LC column portfolio packed in bio-inert hardware, based on two high-efficiency, yet complementary particle platforms and a flexible collection of orthogonal surface chemistries. This new HPLC/UHPLC column portfolio for biologics, aptly named bioZen, focuses on providing improved reproducibility, resolution and performance across major protein characterization techniques.

In this educational webinar, we will introduce the new bio-inert hardware and discuss how it can help save you time, avoid any issues with reproducibility, and improve both the robustness and quality of methods and data.

We will explore:

  • The impact of hardware on sample recovery and priming
  • New HPLC and UHPLC portfolio for analysis of mAbs, ADCs and impurities
  • High molecular aggregate characterization and improved recovery with unique, thermally modified, fully porous SEC columns
  • Improvements in peptide mapping using orthogonal selectivities and particle platforms
  • Top- and middle- down approaches for antibody characterization including average DAR by reversed phase
  • A novel core-shell HILIC stationary phase that offers differentiated released glycan retention profile

Who should attend:

  • Anyone characterizing mAbs, ADCs or biotherapeutics by HPLC/UHPLC
  • Anyone new to the characterization of proteins by SEC, RP, HILIC or IEX
  • Anyone who has a bio-inert UHPLC system
  • Anyone interested in novel HILIC chemistries for N-linked glycan analysis

You can attend the live webinar on Wednesday, May 23, at:

  • 16:00 BST
  • 17:00 CEST
  • 11:00 EDT
  • 08:00 PDT 

Don't worry if you can't make the live event, register to watch on demand at a time that suits you