Drug Discovery Laboratory Application Articles and Drug Discovery Scientific Posters on SelectScience

Drug Discovery /
Application Articles

Analysis of Tricyclic Antidepressants in Human Urine Using UltraPerformance Convergence Chromatography (UPC²)
24 May 2013

Tricyclic antidepressants (TCAs) are an older class of drug traditionally analyzed using GC, UV, or LC/MS. This application note describes the successful implementation of UltraPerformance Convergence Chromatography™ for the analysis of and quantification of four TCAs in human urine. Results demonstrate the utility and benefits of this novel separation technology in the important application area of bioanalysis.

Download this article

Show per page

2 of 25 Page 1 2 3 ... Next

Reverse Phase Protein Arrays for Cell Signaling: Using the InnoScan 710-IR Scanner Improves Sensitivity and Dynamic Range	cell signaling, infrared imaging	17 May 2013	Read
Automation of Illumina TruSeq Exome Enrichment Using the Agilent Bravo Liquid Handling Platform	target-enrichment, NGS, exome sequencing	16 May 2013	Read
High-Resolution Oligonucleotide-Based aCGH Analysis of Single Cells in Under 24 Hours	cancer, copy number variation, genomic hybridization	16 May 2013	Read
Advantages of Online 2D Chromatography for MRM Quantification of Therapeutic Monoclonal Antibodies in Serum	monoclonal antibodies, MRM, therapeutic antibodies	14 May 2013	Read
Multiplex Analysis of Serum Biomarkers in Ovarian Cancer Patients Using Bio-Plex Suspension Array System	tumor, cancer diagnostics, ovarian cancer	14 May 2013	Read
Post-Column Chemistry for Improved Optical Absorption Detection	absorbance reader, EPA methods, trace level impurities	14 May 2013	Read
High Resolution Glycopeptide Mapping of EPO using an Agilent AdvanceBio Peptide Mapping Column	peptides, peptide mapping, glycoprotein	13 May 2013	Read
Peptide Mapping of Glycoprotein Erythropoietin by HILIC LC/MS and RP-LC/MS	peptides, peptide mapping, HILIC	13 May 2013	Read
Accurate and Repeatable Measurement of Fine Crystalline APIs using Laser Diffraction	active pharmaceuticals, particle size analysis, powder analysis	13 May 2013	Read
Analysis of Proliferation Dynamics in Primary and Immortalized Human Cells	cancer cells, cytometry, reporter assay	9 May 2013	Read