TwistDx Limited


TwistDx Limited is a biotechnology company based in Cambridge, UK, and the provider of Recombinase Polymerase Amplification (RPA), a new isothermal DNA amplification and detection technology that is a breakthrough alternative to the Polymerase Chain Reaction (PCR).

RPA is capable of single molecule detection in 10-15 minutes using stable, lyophilised reagents. With increased speed, portability, simplicity of use and PCR-like sensitivity, RPA has become the DNA-based diagnostic platform of the future.

TwistDx makes RPA accessible to end-users in the form of TwistAmp™ kits. The kits are configured with options for electrophoresis, as well as fluorescent and lateral flow detection methods for DNA and RNA targets. TwistAmp™ kits contain all the reagents (apart from target-specific primers and probes) that researchers need to develop their own rapid, highly sensitive and specific RPA assays.

RPA is ideally suited to point-of-care diagnostics for applications including veterinary, food safety, biodefence, agriculture, water testing and clinical, to name just a few.