MerckPTEN hydrolyzes phosphate at the 3 position on the inositol ring of PtdIns(3,4,5)P 3 , and Ins(1,3,4,5)P 4 . Although PTEN has the consensus sequence of a protein tyrosine phosphatase, it dephosphorylates p-nitrophenylphosphate and other s... Read more...