Application Note: Method Development for Size-Exclusion Chromatography of Monoclonal Antibodies and Higher Order Aggregates
2 April 2013

Size-exclusion chromatography continues to be a standard technique for the analysis of monoclonal antibodies and their aggregates. However, as in any SEC method, a thorough evaluation needs to be performed to develop an optimum separation. While HP-SEC can be time consuming, the use of UP-SEC allows method optimization to be predicted in less time with a high level of efficiency and higher degree of confidence.

Download PDF >>PDF Icon

Read the full article...

  Become a member
  • Quick and complete access to all application articles

  • Download 10,000+
    applications and methods

  • Make informed buying decisions

Already a member?

Log in for full access to the article

Remember me