Application Note: Using the NanoDrop 3300 Fluorospectrometer for Cancer Research Applications
3 June 2013
DNA methylation and secondary DNA structures such as DNA G-quadruplexes are among the epigenetic modifications currently under study because of their common associations with cancer. Fluorescence spectroscopy is being used to decipher these complex levels of cellular control at the molecular level, complimenting cell imaging and flow cytometry methods at the cellular level. In addition, fluorescence spectroscopy methodologies are aiding the targeting of and delivery to cancer cells in vivo to correct defects, inhibit growth, or kill cells. This note demonstrates how the NanoDrop 3300 Fluorospectrometer can be used for such applications.