Application Note: SYNAPT G2: A Next-Generation, High-Resolution Time-of-Flight Mass Spectrometry Platform
29 July 2009

Waters introduce the SYNAPT™ G2 System, a new high-resolution quadrupole, time-of-flight MS platform providing a new level of performance for the most challenging MS and UPLC®/MS-based applications. This application note demonstrates the use of orthogonal acceleration time-of-flight (oa-ToF) MS to generate resolution greater than 40,000 (FWHM), which can be used to identify and mass-resolve two isobaric peptides that differ by only 18.2 mDa.