Routine Determination of Glutathione and Glutathione Disulfide using a Novel Boron-Doped Diamond Electrode
15 Jul 2009

Although electrochemical detection is often used for the determination of tissue glutathione (GSH) and glutathione disulfide (GSSG) levels, this approach typically suffers from a number of issues related to chromatography, sample preparation and electrochemical detection. In this application note results indicate that the use of ESA's novel boron-doped diamond (BDD) thin-film electrode can prevent many electrochemical issues. The ability to operate at extreme potentials and resistance to contamination enables the electrochemical detection of thiols and disulfides to be considered routine.

Download this Article




    Popular tags in SelectScience