Application Note: Quality of Cancer RNA Samples is Essential for Molecular Classification Based on Microarray Results
10 April 2007
There are four subgroups of breast cancer, which have a different prognosis and response to chemotherapy. Therefore, correct molecular identification of the subgroups is essential for breast cancer therapy. This application note provides further proof that gene expression profiling for breast cancer classification is a valuable tool, but also suggest that researchers need to consider the potential risks of obtaining misleading classification results when RNA samples of lower quality are used.