Application Note: Organic-Contaminant-Free Water for Ultra-trace Environmental Analysis by Liquid Chromatography-Mass Spectrometry / Mass Spectrometry
1 February 2012

Impurities in the water may easily affect the quality of data produced by LC-MS/MS analysis. This is particularly true of ultra-trace environmental analysis where the contaminants sought may be widely spread in the components and reagents used. This note describes the use and benefits of type I ultrapure water to achieve reliable results. The sensitivity possible with suitably purified water is illustrated with the measurement of sub-ng/l levels of perfluoro-octanoic acid (PFOA) and perfluoro-octanesulphonic acid (PFOS).