Application Note: Non-Contact Acoustic Liquid Dispensing Systems: New Challenges in Automation and Implementation in the Work Flow
10 May 2010
Agilent Automation Solutions has published a technical poster that describes the integration of true non-contact acoustic liquid dispensing technology within an Agilent BioCel System enabling a new level of high throughput automation in a drug discovery environment.
The poster describes the collaboration of Agilent Automation Solutions, EDC Biosystems, and Pfizer Animal Health Division to produce a fully automated compound management solution for screening and developmental assay plates. Automation and throughput requirements demanded that workflows accounted for manipulation of samples in a wide variety of plate formats, such as 384-well, 1536-well, and 3456-well. The objective of the described project was to reduce human manual steps while increasing the capacity and turnaround time of laboratory workflow processes. With this project, the authors describe a protocol to generate 450 compound plates (384 to 384 dispense) per run.
The flexibility of the EDC Biosystem ATS-100 non-contact acoustic liquid dispensing system combined with Agilent Automation Solution's robust BioCel platform and VWorks Automation Control software's ability to use conditional execution while easily integrating with a wide range of third party devices has resulted in a versatile compound management system that can be quickly reconfigured to keep up with Pfizer's rapidly changing needs.