Application Note: Rapid Drug Target Ranking System for Drug Discovery: A Systematic Analysis of Cancer Genomic Data from the Oncomine® Knowledgebase Identifies an Oncogenic Role for the NFE2L2 Pathway in Multiple Cancer Types
7 May 2014

To maximize the value of NGS, it is imperative to develop data analysis/interpretation solutions that accurately assess genomic aberrations, delineate driver alterations from passengers, annotate alterations for potential clinical relevance and integrate alterations by gene and pathway. This poster presents a potential framework for the systematic analysis of thousands of NGS samples as well as expertly curated oncology data for the purpose of identifying potential drug targets.