Application Note: Human Breast Cancer Metastases to the Brain Display Human Breast Cancer Metastases to the Brain Display GABAergic Properties in the Neural Niche
16 February 2014
Dispersion of tumors throughout the body is a neoplastic process responsible for the vast majority of deaths from cancer. A rare Investigation of Breast-to-brain metastatic tissue and cells displayed a GABAergic phenotype similar to that of neuronal cells. The GABAA receptor, GABA transporter, GABA transaminase, parvalbumin, and reelin were all highly expressed in breast cancer metastases to the brain. Images were taken on C-DiGit Chemiluminescent Western Blot Scanner.