Application Note: Contact Lens Biocompatability Studies - Measuring Protein-Polymer Interactions using Dual Polarisation Interferometry
3 November 2009

Dual Polarisation Interferometry (DPI) is an important enabling tool for the study of polymer deposition processes and the molecular mechanisms behind subsequent interactions of proteins and surfactants with the polymer layer. This application note focuses on one area where such studies are of great relevance, the biocompatibility behaviour of polymers commonly used in contact lenses. The system under investigation was HEMA-MA polymer and its behaviour when challenged by the protein lysozyme.