Application Note: Druggability index as a guide for compound synthesis - Analysis of Enamine compound collections
6 June 2006
In this application note the estimated druggability index for the REAL database is calculated according to the approach offered by Sirois, S et al. (Sirois, S.; Hatzakis, G.; Wei, D.; Du, Q.; Chou ,K.C.; Assessment of chemical libraries for their druggabilitiy. Computational Biology and Chemistry, 2005, 29, 55-67). The REAL Database exhibits remarkable values as a source of screening compounds.