Application Note: Direct Analysis of Opioids and Metabolites in Oral Fluid by Mixed-Mode μElution SPE Combined with UPLC-MS/MS for Forensic Toxicology
23 June 2014

This application highlights a method for the analysis of 26 opioid drugs and metabolites by mixed-mode SPE followed by UPLC®-MS/MS. Glucuronide metabolites are directly analyzed, eliminating the need for enzymatic or chemical hydrolysis.

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