Application Note: Development of Assays for High Content Analysis of DNA Damage and Apoptosis
7 November 2009

Histone H2A.X and the tumor suppressor protein p53 have important cellular roles, regulating expression of genes, apoptosis, DNA damage and repair. This application note by Millipore describes a sensitive method for detecting and assessing these key proteins using single- and multi-plex HCA assays, facilitating increased productivity in DNA Damage research, cytotoxicity studies, and drug discovery.