Defining Metabolic Phenotypes in Cancer Cells
3 May 2013

Malignant transformation of cells is often characterized by aerobic glycolysis, the conversion of glucose into lactate, despite the presence of oxygen. Cancer cell bioenergetic analyses have been limited to sequential, independent measurement of cellular respiration, glucose uptake, lactate production and mitochondrial function. While these assays measure parameters of bioenergetic function, they are time consuming, may require the use of radiolabeled reagents and often do not provide real-time data. This application note demonstrates how XF extracellular flux assays can measure both mitochondrial respiration (OXPHOS) and glycolysis simultaneously enabling a rapid and more comprehensive assessment of cellular bioenergetics.

Popular tags in SelectScience

Buying guides

Write a Review

Join the Global SelectScience Community Today! It’s FREE!

Helping you make informed decisions about the latest lab products and technologies:

  • Be the first to learn about new technologies
  • 10,000+ trusted product reviews from your peers
  • Compare 500,000 products and manufacturers
  • Get exclusive buying tips from experts
  • Find solutions fast: 10,000+ Application Notes, Webinars and Videos

Connect with 250,000 scientists... All in one place!

Become a member today!