Application Note: Detecting Copy-Neutral LOH in Cancer using Agilent SurePrint G3 Cancer CGH+SNP Microarrays
1 May 2013

The Agilent SurePrint G3 CGH+SNP microarray platform enables high-resolution CGH analysis, making it a powerful tool for detecting genome-wide copy number and copy-neutral genetic aberrations. This application note demonstrates how CGH+SNP microarrays, when combined with novel computational methods, also enable the determination of clonal fraction, total copy number, and allele specific copy number in aneuploid tumor samples.