Application Note: Application of a New Capillary HPLC-ICP-MS Method for the Identification of Selenium-Containing Proteins in Selenized Yeast
22 October 2013

Diet is the major source of selenium to man, and intake of this essential element depends on the amount of food consumed and the concentration of selenium in food products. Since the levels of selenium in agricultural products are low in many countries, selenium deficiency is a significant problem. A number of supplementation strategies have been developed to increase intake, including selenium-enriched yeast. This application note from Agilent Technologies presents an ICP-MS-assisted proteomic approach for the identification of selenium-containing proteins present in yeast.