Application Note: Agilent Inert Flow Path Enhancements Improve Drugs of Abuse Testing
21 August 2014

This application note presents an evaluation of Siltite versus Agilent UltiMetal Plus Flexible Metal ferrules installed in an Agilent Ultimate Union. Results show improved benzodiazepine peak shape and response for UltiMetal Plus Flexible Metal ferrules by FID. An Agilent 7890/5975C GC/MS Inert Flow Path equipped with a split/splitless inlet showed peak shape and response improvements for the benzodiazepine class of drugs when compared to a standard flow path split/splitless inlet in both SCAN and SIM modes. Example forensic/toxicology check-out mix chromatograms and overlays are presented.