Application Note: Classification of Drugs by CNS Access: An Insight from Quantitative Blood-Brain Transport Characteristics
4 April 2012

The ultimate goal of QSAR analysis focusing on blood-brain barrier penetration is the ability to discriminate between CNS active and inactive molecules. The objective of the current study outlined on this poster was to establish the relationship between quantitative blood-brain transport parameters and qualitative data indicating whether the compound penetrates into the brain efficiently enough to exhibit action in the central nervous system (CNS).

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