High-Resolution Oligonucleotide-Based aCGH Analysis of Single Cells in Under 24 Hours
16 May 2013
As some cells have atypical genomic representation, the ability to analyze individual genomes on microarrays represents a great advancement in cancer and reproductive research. In this application note it is demonstrated how isolated single cells and reference DNA can be processed and analyzed in under 24 hours. The high-resolution, reproducibility, and shorter workflow attained with SurePrint G3 8x60K CGH microarrays allow for the cost-effective analysis of single cell whole genomes for research, overcoming the limitations associated with FISH, PCR-based methods, and BAC arrays.