Application Note: High Content Screening Analysis of Neutrophil Chemotaxis Assays
30 January 2013
Chemotaxis is fundamental to a number of biological processes including the formation of embryonic patterns and migration of immune cells to sites of inflammation and infection. In addition chemotaxis plays a major role in the metastasis of malignant cancers. This application note describes the use of an iuvo™ Chemotaxis Assay technology from BellBrook Labs in combination with TTP Labtech’s acumen hci high-content imager for the study of neutrophil migration. Incorporating the miniaturization of the iuvo™ chemotaxis assay with the “simultaneous data acquisition and analysis” analysis feature of the acumen provides fast data acquisition, thereby enabling increased throughput.