Application Note: Determination of pesticides in baby food by UHPLC/MS/MS using the Agilent 1290 Infinity LC system and the Agilent 6460 triple quadrupole LC/MS
4 November 2011

This application note demonstrates the qualitative and quantitative analysis of pesticides at trace levels in baby food matrices using UHPLC and triple quadrupole MS. Sample preparation is performed for extraction and dispersive SPE. The extracts are analyzed by LC/MS/MS on an LC system coupled to a triple quadrupole LC/MS using Dynamic MRM. The method and extraction performance were evaluated in terms of repeatability, linearity and sensitivity. Moreover the influence of the additional dispersive SPE cleanup was investigated.

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