Application Note: Sensitive Determination of THCCOOH in Hair to Regulatory Requirements Using Triple Quadrupole GC-MS/MS
6 January 2017

This application note details a study in which the analytical setup for determination of THCCOOH in hair using GC-MS triple-quadrupole technology was optimized to obtain maximum sensitivity. The analysis was performed using Thermo Scientific TriPlus RSH Liquid Autosampler mounted on a Thermo Scientific TSQ 8000 Evo GC-MS/MS system. The application note describes the sample preparation technique, set-up of the instruments and the data collections and processing using Thermo Scientific Trace Finder software. It concludes that the system is an extremely effective tool for the routine analysis of THCCOOH in hair samples.