Application Note: Rapid Critical Micelle Concentration (CMC) Determination Using Fluorescence Polarization
11 March 2013

The determination of the critical micelle concentration (CMC) value of surfactants under different environmental conditions is important for a number of different biological and chemical processes. Because the CMC is not a constant value, shifting with different environmental conditions, it is important that a rapid, reliable and easy methodology be available to facilitate testing. This application note describes the rapid semi-automated determination of CMC values for surfactants in 384-well microplates using fluorescence polarization.

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