Natural Products Targeting Oncology Pathways
4 May 2010
In this application note, BioFocus present three examples for natural compounds targeting specific tumor pathways: geldanamycin, borrelidin and fredericamycin. Gram quantities of the compounds are generated using microbial producers and semi-synthesis subsequently generates focused libraries of natural compound analogs. In vivo and in vitro protocols are then used to test potential anticancer properties of the compounds.